proSET Evo Fermentation System

Key Features

  • Duo heating system, thermostat and dry heating combined in one
  • Universal system for R&D in cell culture and microbiology
  • Interchangeable five (5) types of autoclavable glass vessel
  • Control up to sixteen (16) systems from a single interface
  • Compatible with microbial and cell culture applications
  • Intuitive and user-friendly control software in multi-language
  • Small pilot scale 15L and 20L glass vessel compatible
  • Ethernet communication with proSET SCADA software, and IP addressing
  • proSET EZScript software for advanced fermentation process (optional)

SKU: CSFS-07

SKU: CSFS-07 Category:
Special Requirements?

Description

proSET Evo System is the newest fermentor that offers an all-in-one fermentation solution and ultimate automation experience to ensure easy, smooth and productive bio-processing. The controller is pre-configured to support both thermostat and dry heating; together with its full compatibility to vessels from 0.5 to 20L, it provides a broad coverage to cultivation of most cell lines.

proSET Evo System is equipped with the latest control software; this user-friendly, intuitive software incorporates with many advanced functions to boost your experiment efficiency and thus lead to the success. Besides the manual controls of agitation, temperature, pH, DO level and feeding, one can also execute 15-step scheduled sequence controls on above parameters as well as pH and DO feedback controls. Moreover, a broad selection of plug-and-play optional devices are available to meet your specific requirement.

 PC software connects up to 16 systems & 16 vessels at the same time.

This unit has a 12 month limited warranty, for more information, consult our terms and conditions.

Control unit Control panel 10.4” color touch-screen Interface (Resolution: 800 x 600 pixels)
 Communication port Remote control through Ethernet
 Data export through USB port
 Analog AUX port for system extension
Number of vessels controlled per remote control software Max. 16
 Program storage Up to 59,994 programs for different kinds of condition
 Log data storage Up to 100 process monitoring data files
 Cabinet material ABS front panel and painted iron housing
 Dimension Footprint: W x D = 15.75" x 22.44" (400mm x 570mm); Height: 29.14" (740mm)
 Rated voltage 110V~/220V~; 50/60 Hz, 10A
Aeration Inlet gas flow-meter 0, 0.1-1LPM (0.5L); 0, 0.4 - 5LPM (1L); 0, 1 - 10LPM (3, 5L);  0, 2 - 20LPM (10L); 0, 4 – 50LPM (15, 20L)
 Sparger Orifice ring
 Baffle Removable 316L stainless steel baffles
TemperatureHeating 1. Thermostat System: built-in heat exchanger  (550W heater, water circulation pump)
 2. Dry heating system (heating blanket or heating base unit)
Cooling Cooling coil valve
 Range with FS-V-A / B / C series : 5°C (41°F) above coolant up to 60°C (140°F);  with FS-V-D series :5°C(41°F) above coolant up to 90°C  (194°F);
 Probe Platinum RTD probe (PT-100), non autoclavable
 Control mode Manual or Programmable 15 steps PID control
Agitation Drive Removable top brushless motor (M3 for 0.5L, 1L; M2 for 3~20L)
 Speed range a. For extremely shear-sensitive cell line: 30-300rpm  b. For fermentation and cell culture: 30 - 1200rpm (0.5-5L); 30 - 1000rpm (10L);      30 – 700rpm(15, 20L)
 Resolution 1rpm
 Impeller 2 impellers for 0.5L &1L vessel and double jacketed vessels   3 impellers for 3L vessel and above   Note: Customized impellers are available upon ordering
 Control mode Manual or Programmable 15 steps PID control
pH Range 2 - 14pH
 Resolution 0.01pH
 Probe Gel-filled electrode, autoclavable
 Control mode Manual/programmable 15 steps PID control with adjustable deadband,  pH stat with smart feeding technology
DO   Range 0 - 200%
 Resolution 0.10%
 Probe Polarographic DO sensor; autoclavable
 Control mode   2-stage DO cascade response  a. Increase or decrease agitation speed   b. Oxygen Enrichment module(Optional)  c. Gas Mixing Station module(Optional)  DO stat with smart feeding technology
ORP(optional) Measurement range -/ 2000mV
 Resolution 1mV
 Probe Gel-filled electrode: autoclavable    
Foam / Level Probe 316L stainless steel protector with insulated PTFE tube, autoclavable, adjustable sensitivity control
Control Mode Foam: On/Off switch  Level: On/Off switch control with wet/dry probe set up
Peristaltic PumpPump number 4 x built-in pumps, 1 to 2 external pumps (Optional)
 Motor type Precise stepping motor; minimum speed is 1rpm
 Speed range 0 to 65rpm
 Resolution 1rpm
 Control mode Manual or Programmable 15 steps feeding control; pump can be assigned  for Acid, Base,        Antifoam and/or Substrate; pump can calculate flow rate and total volume
ExhaustDevice type 316L stainless steel condenser
System Specification
ControllerDuo heating system controller
Built-in rotameter
4 x built-in pump heads
VesselDouble jacketed vessel (includes glass body, head plate, T-handling bar, 2 probe adaptors)Single wall dish bottom vessel (includes glass body, head plate, T-handling bar, 2 probe adaptors)Airlifter vessel (includes glass body, head plate, draft tube, T-handling bar, 2 probe adaptors)Single wall dish bottom with heating blanket (includes glass body, head plate, T-handling bar, 2 probe adaptors and heating blanket)Single wall plain bottom with heating base unit (includes glass body, head plate, T-handling bar, 2 probe adaptors and heating base unit)
2 adjustable Pitched-blade impeller3 adjustable Rushton-type impellersno impellers3 adjustable Rushton-type impellers3 adjustable Rushton-type impellers
Baffle assembledDraft tube assembledBaffle assembled
Condenser assembled
Air sparger assembledMicro sparger assembledAir sparger assembled
MotorAgitation motorN / AAgitation motor
Probes1x pH probe and 1x pH cable
1x Do probe and 1x DO cable
1x Temperature probe and 1x Temperature cable
1x anti-foam/level sensor and 1x anti-foam/level sensor cable
Start-up KitComplete start-up kit includes, silicone tubes, tube clamps, metal connector and autoclavable disc filters
Vessel Specification
VesselDouble Jacketed (FS-V-A series)Single Wall (FS-V-B series)Air Lifter (FS-V-C series)
Working volume500ml1L3 L5 L10 L1L3 L5 L10 L5 L
Total volume1L1.5L3.8 L6.8 L12.5 L1.5 L3.8 L6.8 L12.5 L7 L
 
VesselSingle Wall with Heating Blanket (FS-V-B series)Single Wall with Heating Base Unit (FS-V-D series)
Working volume1L3 L5 L10 L15L20L3 L5 L10 L
Total volume1.5L3.8 L6.8 L12.5 L18L24.4L3.7 L6.4 L13.4L
Utility Requirement
Power source100-120V / 210-230V, 50-60Hz with electrical safety cutoff switch
Water source10 psig (0.69 barg), 14.5 psig (1 barg) maximum; (water supplied to fermenter must be softed and at least 15°C below set operating temperature)
Air source10 psig (0.69 barg), 29.0 psig (2 barg) maximum; air must be dry, oil-free and filtered
SterilizationAutoclave; size of the autoclave inner chamber must be able to accomodate vessel with condenser attached

This product has been cited in the following research papers:

Reference titleDateCitationProduct usage
Biosynthesis of chitosan-Oligosaccharides (COS) by non-aflatoxigenic Aspergillus sp. strain EGY1 DSM 101520: A robust biotechnological approach2018Amira M. Embaby, Ramy R. Melika, Ahmed Hussein, Amal H. El-Kamel, Heba S.Marey, Process Biochemistry, Volume 64, January 2018, Pages 16-30,…Fig. 4. Batch cultivation of Aspergillus sp. section Flavi strain EGY1 DSM 101520 in a laboratory scale fermenter. Production medium (4 liters) with an initial pH of 5.0 in a 7-liters Cleaver laboratory scale fermenter was inoculated with 5% (v/v) seed culture previously grown for 72 h at 30 °C. The process was conducted at 25 °C under automated controlled pH. Each data point is expressed as the a…
Scaling-Up of Natural Products Isolation2012Cite this protocol as: Kumarasamy Y. (2012) Scaling-Up of Natural Products Isolation. In: Sarker S., Nahar L. (eds) Natural Products Isolation. Methods in Molecular Biology (Methods and Protocols), vol 864. Humana Press… useful feature of this system is that it is available with interchangeable vessels which range from 2.2 L to 14.0 L. Other companies that produce similar fermentors include Minifors®, Lavalabs®, and Cleaver Scientific. Bench-top fermenters are usually cheaper to purchase than the trolley mounted or skid-mounted fermenters. The entry level fermentors are simple in construction and can be thought o…